Suburban Seattle, the mid-1970s. We learn from the outset that a strange plague has descended upon the area's teenagers, transmitted by sexual contact. The disease is manifested any number of ways - from the hideously grotesque to the subtle (and concealable) - but once you've got it, that's it. There's no turning back.
As we inhabit the heads of several key characters - some kids who have it, some who don't, some who are about to get it - what unfolds isn't the expected battle to fight the plague, or bring heightened awareness of it, or even to treat it. What we become witness to instead is a fascinating and eerie portrait of the nature of high-school alienation itself - the savagery, the cruelty, the relentless anxiety and ennui, the longing for escape.
And then the murders start.
As hypnotically beautiful as it is horrifying (and, believe it or not, autobiographical), Black Hole transcends its genre by deftly exploring a specific American cultural moment in flux and the kids who are caught in it - back when it wasn't exactly cool to be a hippie any more, but Bowie was still just a little too weird.
To say nothing of sprouting horns and moulting your skin...